Former rugby players Doddie Weir and Rob Burrow, who have MND, were among those calling on the government for more investment.
The government has announced it will put at least £50m over five years into research in a bid to find a cure.
Ex-Leeds Rhinos’ scrum-half Burrow said “the hard work starts now… to find an effective treatment”.
Speaking to BBC Breakfast, he said he felt “on top of the world”, knowing “that someone is listening to us”.
Former Scotland Rugby Union international Doddie Weir said the money was going to make a “huge difference not only to the patients, but also the MND patients’ families as well”.
MND affects the brain and nerves, eventually stopping muscles functioning.
Ex assistant chief constable Chris Johnson, who also has the condition, told the BBC the announcement by government was a “monumental decision”.
The 54-year-old, from Bromsgrove, was diagnosed with the disease in 2018 and retired from West Midlands Police last year.
“I think this offers some hope to the MND community across the country. We hope it can move from a terminal disease to a treatable one within the [five-year] time frame,” he said.
Speaking to the BBC in September, Mr Johnson said while his condition had deteriorated, he felt “blessed” to have seen another Christmas with his family and spend birthdays with his children.
He said many others with MND died within two years of diagnosis.
“Motor neurone disease doesn’t discriminate, whether it’s age, whether it’s religion, whether it’s around your nationality, it truly is a disease for everybody,” he said at the time.
An open letter to government, signed by hundreds of MND sufferers and delivered in September, said the condition was currently a “death sentence”, but research had reached a point where a cure or life-saving treatment could be found.
It also said the disease was “not rare”, as it would kill one in 300 people in the current population.